局部氧疗促进下肢慢性创面愈合临床观察:下肢动脉造影创面多大

　　[摘要]目的:观察局部氧疗辅助治疗下肢慢性创面愈合的临床疗效。方法:2004年4月～2009年11月,50例下肢慢性创面不愈合患者,随机分成常规治疗组(A组)和常规治疗加局部氧疗组(B组)。A组30个患者42个创面,给予常规治疗;B组20个患者30个创面,在常规治疗的基础上每天局部氧疗1次,持续90min,每周治疗5天,4周一疗程。比较两组创面愈合所需的时间,创面愈合百分率,治疗有效率,并作统计学分析。结果:A组创面愈合时间分别为(25.3±7.6)天,B组为(18.2±5.8)天;A组创面愈合百分率为(71.8±12.1)%,B组(96.1±5.6)%; A组创面治疗有效率为71.4%,B组为100%;所有对比项目在两组之间的差异均有统计学意义(P 　　1.2 方法
　　1.2.1 常规治疗:①预防和控制感染:对两组患者创面均行彻底清创,清除坏死组织,双氧水、生理盐水反复冲洗创面,清除创面中分泌物。根据分泌物病原菌培养及药物敏感试验结果选择抗生素;②控制血糖:对糖尿病患者在治疗期间均给予糖尿病饮食及胰岛素治疗,控制空腹血糖 　　[5]Hopf HW, Rollins MD. Wounds: an overview of the role of oxygen [J]. Antioxid Redox Signal,2007,9(8):1183-1192.
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　　[收稿日期]2009-10-21[修回日期]2010-01-19
　　编辑/张惠娟