癜痫病不吃药5年没发作_自拟定痫丸联合拉莫三嗪治疗难治性癫痫疗效观察

　　[摘要] 目的 观察添加自拟定痫丸联合拉莫三嗪对难治性癫痫的临床效果和生活质量的影响。方法 癫痫病人68例，随机分为拉莫三嗪组和加用自拟定痫丸联合拉莫三嗪组，并在用药前、后1年进行疗效及生活质量评价，按常规计算有效率。结果 病人用药依从性好，总有效率分别为52.9%和70.6%,差异显著性(p�0.01)，生活质量明显提高,(p�0.05-0.01),两组均未见特殊毒性反应。结论 自拟定痫丸联合拉莫三嗪能显著减少发作频率，改善认知功能，提高生活质量，安全耐受性好，是安全有效的方法之一。
　　[关键词] 难治性癫痫 自拟定痫丸联合拉莫三嗪 临床效果 生活质量
　　[中图分类号] R742.1[文献标识码] A[文章编号] 1005-0515（2011）-08-007-01
　　[Abstract] Objective To observe the combined pill to add from the development of lamotrigine for refractory epilepsy effects and quality of life.Methods 68 cases of epilepsy patients were randomly divide into groups and processing LTG formulation pill combined with a self-lamotrigine group and before and after 1 year treatment evaluate the efficacy and quality of life according to conventional calculation efficient.Results The patients compliance good medicine, the total effective rate was 52.9% and 70.6%, the difference was significant (p